Fantastic Four #15
DOOMED! Part 3: The Elements of War
The Fantastic Four struggle to stop the molecular plague destroying their powers and bodies.
Standing between them and the cure: the Frightful Force, an army of their greatest foes, led by one of the F4's own who betrayed them! Their only allies: another Fantastic Four!
Meanwhile, Dr. Doom, Kang, and Annihilus come to an ominous meeting of the minds...