When the evil Inheritors begin exterminating spider-characters throughout the multiverse, every single Spider-Man ever is needed to save the day! An interdimensional spider-army gathers to fight Morlun and his deadly family, but none of them is safe as the Prophecy comes to fruition! What will this brutal war for survival mean for Peter Parker and the rest of the spiders? Starring the Superior Spider-Man, the Ultimate Universe's Miles Morales and Jessica Drew, Spider-Man 2099, Spider-Woman, Silk, Kaine, Scarlet Spider, MC2's Spider-Girl, Spider-Man Noir, Spider-Man 1602, Spider-Ham, Spider-Monkey, Lady Spider, Spider-Punk, Spider-UK, a spider-powered Gwen Stacy...and hundreds more, from the beloved to the obscure! Collecting AMAZING SPIDER-MAN (2014) #7-15, SUPERIOR SPIDER-MAN #32-33, SPIDER-VERSE #1-2, SPIDER-VERSE TEAM-UP #1-3, SCARLET SPIDERS #1-3, SPIDER-WOMAN (2014) #1-4, SPIDER-MAN 2099 (2014) #6-8 and material from FREE COMIC BOOK DAY 2014 (GUARDIANS OF THE GALAXY) #1.